Tea tree (Melaleuca alternifolia) is a perennial evergreen shrub or small tree native to the coastal regions of New South Wales and Queensland in Australia. The plant has narrow, needle-like leaves that are rich in essential oils and small, white to pale yellow flowers that bloom in dense clusters. Tea tree thrives in swampy, lowland areas and is well-adapted to the Australian climate, with a preference for wet, marshy conditions and sandy soils.
In traditional and modern medicine, tea tree oil, extracted from the leaves of the plant, is highly valued for its therapeutic properties. In Australian Aboriginal medicine, it has been used for centuries to treat wounds, cuts, and infections. In contemporary herbal medicine, tea tree oil is renowned for its antiseptic, antibacterial, antifungal, and anti-inflammatory properties. It is a common ingredient in topical formulations for treating acne, dandruff, insect bites, and minor cuts and abrasions. It is used in aromatherapy to alleviate respiratory issues and boost the immune system. In Western medicine, tea tree oil is incorporated into a variety of over-the-counter products, including skin cleansers, shampoos, and ointments, reflecting its broad-spectrum antimicrobial efficacy.
The primary active ingredient in tea tree oil is terpinen-4-ol, which is largely responsible for its potent antimicrobial activity. Other significant compounds include α-terpinene, γ-terpinene, and 1,8-cineole. Terpinen-4-ol disrupts the permeability of microbial cell membranes, leading to cell lysis and death, making it effective against a wide range of bacteria, fungi, and viruses. α-Terpinene and γ-terpinene contribute to the oil's overall antimicrobial spectrum, enhancing its effectiveness.